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Coach Kolt | Hypertrophy & Nutrition Coach on Instagram: "Calcium ion fatigue: excitation contraction coupling failure - Calcium ions are required for muscle contractions. Mitochondria help clear it out, but after repeated contractions, mitochondrial overload happens. Poteases and calpains activate and start breaking the bridge (junctophilin 2) between the roads (T tubules) and the water tower (sarcoplasmic recticulum). Action potentials from the brain can no longer reach the water tower and tha
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Coach Kolt | Hypertrophy & Nutrition Coach on Instagram: "Calcium ion fatigue: excitation contraction coupling failure - Calcium ions are required for muscle contractions. Mitochondria help clear it out, but after repeated contractions, mitochondrial overload happens. Poteases and calpains activate and start breaking the bridge (junctophilin 2) between the roads (T tubules) and the water tower (sarcoplasmic recticulum). Action potentials from the brain can no longer reach the water tower and tha
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