As the most upstream component of the renin-angiotensin-aldosterone system, angiotensinogen represents an attractive target ...

Cardiovascular diseases account for approximately 30% of deaths worldwide and remain a leading cause of morbidity and ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

BACKGROUND: Classically, hypertrophic cardiomyopathy (HCM) has been viewed as a single-gene (monogenic) disease caused by ...

Background: In severely symptomatic patients with obstructive hypertrophic cardiomyopathy (HCM), VALOR-HCM trial (Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are ...

View all available purchase options and get full access to this article. Wagner R, Heni M, Tabak AG, Machann J, Schick F, Randrianarisoa E, Hrabe de Angelis M, Birkenfeld AL, Stefan N, Peter A, et al.

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Almost everyone who first sees moving heart walls, valves, and flows by echocardiography experiences fascination and wonder. Echocardiography is unique among cardiac imaging modalities because It ...

Department of Internal Medicine (Q.S., J.W., H.M., X.L., J. Streeter, J. Sharafuddin, E.W., B.C., D.H., L.-S.S., E.D.A.), Carver College of Medicine, University of ...