The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

San Francisco 49ers running back Isaac Guerendo is expected to play in Thursday's pivotal game against the LA Rams, according ...

The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

No team has dealt with more injuries at the running back position this season than the San Francisco 49ers. The Los Angeles ...

Linebacker Dre Greenlaw is cleared to suit up again for the 49ers tonight, 10 months after tearing his left Achilles in the ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

Rookie running back Isaac Guerendo is not participating in Tuesday's practice session with the San Francisco 49ers. Guerendo ...

San Francisco 49ers running back Isaac Guerendo has a foot sprain, per head coach Kyle Shanahan. 49ers HC Kyle Shanahan said ...

The Los Angeles Rams will take on the San Francisco 49ers in Week 15 of the NFL season on Thursday. This prediction is based ...