San Francisco 49ers QB Brock Purdy stepped up in the pocket and delivered a 16-yard strike to rookie WR Ricky Pearsall ...

Los Angeles Rams outside linebacker Byron Young engulfs San Francisco 49ers running back Isaac Guerendo on an authoritative tackle for a loss in the rain.

No one could have expected the San Francisco 49ers to be in this position so late into the 2024 season. The 49ers are 6-7 on the year, sitting tied for last pla ...

Deebo Samuel after his rough outing included tackling his own teammate, bad stats and dropping an easy touchdown.

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

The Los Angeles Rams and San Francisco 49ers square off on "Thursday Night Football" to start Week 15 of the NFL season. Of ...

San Francisco 49ers rookie running back Isaac Guerendo (foot) is officially active for Thursday night's divisional clash in ...

Micah Roberts, on a 26-6 run on 49ers picks, has revealed his Week 15 Thursday Night Football expert picks for Los Angeles vs ...

The 49ers will have defensive lineman Nick Bosa, linebacker Dre Greenlaw and running back Isaac Guerendo for Thursday Night Football.

The Los Angeles Rams and San Francisco 49ers both came into tonight’s game with injury questions, each listing several ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are set to make their return from injury versus ...