The 49ers season ends with a 47-24 defeat that showcases all the reasons they lost 11 games. A gassed defensive line gives up 21 points in the 4th quarter.

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted San Francisco 49ers 47-24.

George Kittle ’s wife, Claire Kittle, expressed her take on the NFL star’s outfit ahead of the San Francisco 49ers ' game ...

The NFL was once again the dominant force on American television in 2024 as viewers sat down in huge numbers to watch the ...

Here's who local and national NFL analysts are picking to win Sunday's season finale between the Bears and Packers at Lambeau Field.

The NFC’s No. 1 seed, two division titles and two playoff spots are on the line in Week 18. Game No. 272 on Sunday night ...

Police in San Francisco have made an arrest after a man was fatally shot in the city's Mission District shortly after the ...

A PG&E outage on Tuesday afternoon was affecting over 4,000 customers in San Francisco, according to the utility’s outage map ...

A new batch of laws targeting crimes that have increased a “sense of social anxiety” among Californians reflects support for stronger penalties following a decade of ...

ESPN's cameras caught San Francisco 49ers general manager John Lynch raging at his team during Monday night's loss to the ...

On the opening possession of the game, the 49ers marched down the field on an 11-play, 61 yard drive they finished with a ...

In a game they didn’t have to win, the Detroit Lions still went into San Francisco and outscored the 49ers on Monday Night ...