The firm saw an improvement in progression-free survival for patients on the ivonescimab regimen and a trend toward improved overall survival.

Phase III progression-free survival data were positive for first-line Braftovi in first-line combination therapy for mCRC.

Effect of Metformin Versus Placebo on New Primary Cancers in Canadian ... of pretreatment tumor HER3 membrane expression levels and across diverse mechanisms of EGFR TKI resistance. In patients with ...

Metformin is the most commonly prescribed oral treatment for type 2 diabetes mellitus (T2DM), a condition prevalent in patients with cardiovascular diseases. Since LCZ696 and metformin may be ...

Multivariable logistic regression was used to identify populations eligible for metformin (i.e., eGFR ≥45 mL/min/1.73 m 2 among individuals with creatinine levels above conventional sCr cutoffs.

Merus N.V., an oncology-focused company, announced the publication of research on petosemtamab, a bispecific antibody targeting EGFR and LGR5, in the journal "Cancers." The study highlights the ...

In acute kidney injury, certain biomarkers—such as urine albumin-to-creatinine ratio and epidermal growth factor—are linked with likelihood of eGFR nonrecovery. Serum creatinine elevations during ...

Metformin was tested in the 1940s as a treatment for malaria, well before it became a mainstay of type 2 diabetes management. It’s since been investigated for its effect on weight, fertility, various ...

Purpose: To investigate the correlation between single-nucleotide polymorphisms (SNPs) of the Epidermal growth factor receptor (EGFR) gene and its protein expression with susceptibility and survival ...

Afatinib (Afa) + bevacizumab (Bev) versus afatinib alone as first-line treatment of patients with EGFR-mutated advanced non-squamous NSCLC: Primary analysis of the multicenter, randomized, phase II ...

India hits Lahore's Air Defence Radars in proportionate response Pakistan tried to hit military targets in these 15 Indian cities, New Delhi thwarts strikes This surprising turn of events may be a ...