Metformin and lifestyle intervention was associated with delayed type 2 diabetes onset and slower diabetes progression than placebo.

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat.

In a study of older adult women with diabetes led by UC San Diego researchers, metformin, a widely used diabetes medication, ...

The research on metformin and human longevity is scant, but that hasn’t stopped some people from experimenting with it. By Mohana Ravindranath A few years ago, Marc Provissiero, a movie producer ...

We performed subgroup analyses stratified by sex, age, estimated glomerular filtration rate (eGFR), and baseline diuretic use. Two separate linear regression analyses were performed to assess the ...

Researchers have found in a new study that patients receiving a combination of metformin and SGLT2 inhibitors experienced ... 40% reduction in estimated glomerular filtration rate (eGFR) or end-stage ...

The increasing popularity of weight loss drugs like Wegovy®, Ozempic, Mounjaro and metformin may have you wondering how all these options stack up. Are there benefits to one over the other?

“Metformin undergoes rapid renal excretion without metabolism, and prescription rates are low in patients with reduced GFR due to the risk of lactic acidosis, a rare side effect caused by ...

People with acute kidney injury should stop or avoid taking metformin. If you’re already taking it, speak with your doctor before stopping. If your GFR is between 46 and 60, your dose should be ...

Metformin use decreased with advanced CKD stages ... SGLT2i and GLP-1 RA were less used in patients with advanced eGFR stages but were more frequently used in patients with elevated uACR ...