Isaac Guerendo took advantage of his first NFL start ... The group protected Brock Purdy, allowing only six pressures. Here are the 49ers' PFF grades for Week 14: TE George Kittle - 91.7 Kittle ...

San Francisco's PFF grades from the 40-34 defeat show high ... The running game was less productive, even with Isaac Guerendo’s return and Deebo Samuel and Pearsall's contributions.

San Francisco 49ers rookie running back Isaac Guerendo's 15-yard rushing score gives the 49ers their first touchdown of their "Sunday Night Football" road game against the Buffalo Bills in Week 13 ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class ...

San Francisco 49ers running back Isaac Guerendo's second touchdown of day gets 49ers to 30-point mark vs. Chicago Bears. Watch the highlights from Super Bowl LIX between the Kansas City Chiefs and ...

San Francisco 49ers running backs Christian McCaffrey and Isaac Guerendo had good news on their late-season injuries, and both appear to be on track to be ready for the start of the 2025 season.