Example: An example of the metabolite identification process using MyCompoundID. Table S1: List of 76 commonly encountered metabolic reactions. Table S2: List of metabolite peaks detected in a human ...

Department of Pharmacology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, ...

Cells change their metabolic profiles in response to underlying gene regulatory networks, but how can alterations in metabolism encode specific transcriptional instructions? Here, we show that forcing ...

Further exploration of the antidepressant mechanisms of ketamine will contribute to its safe and practical application. Metabolites, the products of upstream gene expression and protein regulatory ...

Gallic acid (GA), a natural secondary metabolite found in various fruits, plants, and nuts, has demonstrated potentials in preventing and treating ASCVD, in addition to its known antioxidant and ...

In this editorial, the authors describe the foundations of an N-of-1 gene-editing study to treat an infant with a urea-cycle disorder. 2 Department of Chemistry and Biochemistry, University of ...

Secondary metabolites are a reliable and very important source of medicinal compounds. While these molecules have been mined extensively, genome sequencing has suggested that there is a great deal ...

A new study has identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia. The paper is published in Nature ...

Coffee may affect how a medication is absorbed, metabolized or removed from the body. An expert shares the seven drugs, like asthma and cold medications, that interact with coffee. For the ...