San Francisco 49ers running back Christian McCaffrey (23) runs against Buffalo Bills safety Taylor Rapp, bottom, during the first half of an NFL football game in Orchard Park, N.Y., Sunday ...

San Francisco 49ers running back Christian McCaffrey suffered an apparent non-contact lower leg injury on Sunday Night ...

It would appear Christian McCaffrey's 2024 campaign is ending less than a month after it began. San Francisco 49ers head coach Kyle Shanahan told reporters after Sunday night's game that McCaffrey ...

Christian McCaffrey, at the premature end of a season that started late, too, waxed philosophical in a social media post on ...

Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football ...

ORCHARD PARK, N.Y. -- San Francisco 49ers running back Christian McCaffrey suffered what is believed to be an injury to the posterior cruciate ligament in his right knee Sunday night, leaving the ...

The San Francisco 49ers might be without their Steph Curry for the rest of tonight's game against the Buffalo Bills. Head coach Kyle Shanahan likened star running back Christian McCaffrey to the ...

This has been a forgettable season for Christian McCaffrey ... star running back joined a few of the 49ers’ other standouts in being out of the mix. McCaffrey left Sunday’s blowout loss ...