We have developed differential gene expression data sets from breast tumors through analysis of 8 in situ and 32 invasive breast tumors relative to 6 samples of normal breast tissue using arrays ...

Cells begin to accumulate centrosomes-;organelles that play a vital role during cell division-;before they transform into cancer cells, according to a new study of patients with Barrett's esophagus ...

R. Basto et al., “Centrosome amplification can initiate tumorigenesis in flies,” Cell, 133:1032–42, 2008. (Cited in 32 papers) Tumor cells display both chromosomal instability and centrosome ...

Cells begin to accumulate centrosomes -- organelles that play a vital role during cell division -- before they transform into cancer cells, according to a new study of patients with Barrett's ...

An MUSC Hollings Cancer Center research team has identified a protein that helps cancer cells to organize themselves in a way that allows them to successfully navigate the cell division process ...

Intra-patient genomic heterogeneity of single circulating tumor cells (CTCs) associated to phenotypic CTC heterogeneity in metastatic castrate resistant prostate cancer (mCRPC). SOD2 rs4880 CT/CC ...

The paper M.S. Levine et al., “Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals,” Dev Cell, 40:313-22, 2017. Three’s a crowd More than a century ago, the German ...

Accurate control of the number of centrosomes, the major microtubule-organizing centers of animal cells, is critical for the maintenance of genome integrity. Abnormalities in centrosome number can ...

Centrosome duplication is tightly controlled in co-ordination with DNA replication. The molecular mechanism of centrosome duplication remains unclear. Previous studies found that a fraction of human ...

Bisphenol A May Boost Prostate Cancer Risk Elevated urinary levels of the organic compound were found in men with prostate cancer than in those without it. Findings from a recent study suggest that ...

Cells begin to accumulate centrosomes—organelles that play a vital role during cell division—before they transform into cancer cells, according to a new study of patients with Barrett’s esophagus ...