The study also raises the possibility of exploring the autophagy-ferroptosis axis in other cancers that metastasize to the bone. Dr. Aline Bozec, the lead investigator of the study, commented ...

To determine whether HGF/Met axis underwent DNA-methylation control and played a crucial role in bone metastasis outgrowth, we first studied Met pattern by immunohistochemistry under dAza (Figure 2).