The 49ers are in a good spot to land pass rush help … or Ashton Jeanty … in the 1st round of this year’s draft.

Christian McCaffrey suffered what turned out to be a season-ending knee injury in the San Francisco 49ers’ Week 13 loss to ...

San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...

After missing San Francisco's Week 16 loss to the Miami Dolphins, 49ers rookie running back Isaac Guerendo reportedly is ...

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

Olivia Culpo, the wife of San Francisco 49ers star Christian McCaffrey, posted on social media early Wednesday thanking the "heroes" battling the wildfires raging through southern California.