Family runs deep in the NFL, and two San Francisco 49ers captains showed that their support extends beyond team colors.

The 49ers were already out of playoff contention, and the Lions had little to play for, but that didn’t stop fans from tuning in on Monday night. Lions-49ers was the most-watched Monday Night Football ...

Jared Goff threw three touchdown passes and the Lions tuned up for their Week 18 division showdown against Minnesota by beating the 49ers 40-34 on Monday night. “That’s the only way we know.

The 49ers remain in the No. 11 overall spot after their "Monday Night Football" loss to the Detroit Lions, another NFC West matchup reshuffled the draft order. The Cardinals' 13-9 loss to the Los ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

The Lions (14-2) took down the San Francisco 49ers (6-10) 40-34 at Levi's Stadium in a high-scoring win. Detroit got a win on the same field where their 2023 season came to an abrupt end one game ...

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?

Yes, some of the luster has rubbed off the Detroit Lions’ matchup tonight with the San Francisco 49ers. The rematch of January’s NFC championship game — have you heard? — is more for ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

The San Francisco 49ers have taken a significant step back in 2024, and one ESPN analyst believes that’s because of Kyle Shanahan. San Francisco was eliminated from playoff contention with ...

And yet you guys managed to bring thoughtfulness — and even some mirth — to this week’s San Francisco 49ers holiday mailbag. Well done! I hope your stockings were full of frankincense and myrrh.