Despite a dominant win over the Bears, the 49ers face an uphill battle to secure a playoff spot with four games remaining.

Bears interim coach Thomas Brown discusses the two injury issues for the Bears and also his first opportunity to lead the ...

Brock Purdy's injury update: 49ers in trouble? The San Francisco 49ers are gearing up to face the Buffalo Bills on Sunday Night Football in what promises to be one of the coldest games in recent ...

when Purdy was listed as questionable with a shoulder injury but declared the starter by coach Kyle Shanahan to face the Bills. “I feel good, so I’m excited to be able to play,” Purdy said before the ...

San Francisco 49ers quarterback Brock Purdy has been dealing ... injury but declared the starter by coach Kyle Shanahan to face the Bills. “I feel good, so I’m excited to be able to play ...

San Francisco 49ers running back Christian McCaffrey (23) stops Green Bay Packers linebacker Quay Walker (7) during the second half of an NFL football game on Sunday, Nov. 24, 2024 in Green Bay ...

The San Francisco 49ers may have their starting field general back for their Week 13 Sunday Night Football clash with the Buffalo Bills, but they’ll be without their pivotal left tackle and pass ...

so Wednesday's limited session suggests he could return as soon as Sunday's matchup against the 49ers. Brown's practice participation Thursday and Friday will likely provide the best indication of ...

Conversely, if the 49ers fail to make the playoffs with this schedule, there can be no argument on letting Shanahan go. Purdy’s fate changes with the Shanahan uncertainty going forward.

It remains to be seen who will and won’t be available when the 49ers embark on a cross-country trip to face the AFC East-leading Bills, currently 9-2 and the No. 2 seed in the conference.