DETROIT -- The Buffalo Bills came out of halftime with a lead and the ball. Less than two minutes later, the Bills offense ...

Sean McDermott? The Buffalo Bills head coach will join elite coaching company with a win over the Los Angeles Rams on Sunday.

The Bills and 49ers meet on Sunday Night Football in a game with playoff implications for both teams. Here are three ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The Buffalo Bills head coach will join elite coaching ... including six straight with at least 11 wins from 1976-1981. Dungy retired on a run of six consecutive 12-plus win seasons with the ...

The 49ers were a perennial power as they won five Super Bowls between 1981 and 1994 and reached ... “Nobody circles the wagons like the Buffalo Bills!” Sign up for the Bills Blast ...

Buffalo-born author Ed Park's book, "Same Bed Different Dreams," was a finalist for this year's Pulitzer Prize for Fiction.

Thousands of flights have been delayed after a massive snowstorm hit the Great Lakes region. NBC News’ George Solis reports from the Buffalo Bills stadium where several feet of snow will fall this ...

Former LSU and Buffalo Bills star Kyle Williams is still the Ruston defensive coordinator. He has a nephew set to play for a ...

ORCHARD PARK, N.Y. (AP) — San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” season-ending in the 49ers’ 35-10 loss ...

Of immediate interest is the potential impact on post-Thanksgiving travel and the Sunday Night Football game in Orchard Park between the Buffalo Bills and ... Not Used Since 1981 CFB Week 14 ...

"It can be argued that no one represents the history of local television news in Western New York more than WIVB-TV (Channel ...