Objectives MAXIMISE (Managing AXIal Manifestations in psorIatic arthritis with SEcukinumab) trial was designed to evaluate the efficacy of secukinumab in the management of axial manifestations of ...

Background An important but often insufficient aspect of care in people with inflammatory arthritis (IA) is empowering patients to acquire a good understanding of their disease and building their ...

Background Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical ...

Objectives Clinical heterogeneity is a cardinal feature of systemic sclerosis (SSc). Hallmark SSc autoantibodies are central to diagnosis and associate with distinct patterns of skin-based and ...

Background The primary cilium is a microtubule-based, polarized, antenna structure that emanates from the cell surface of most mammalian cell types. It serves as a sensor that mediates reactions to ...

Objective Dactylitis is a hallmark of psoriatic arthritis (PsA) where flexor tenosynovitis is common. This study explored the microanatomical basis of dactylitis using high-resolution MRI (hrMRI) to ...

Objectives: To investigate dynamics of B-cell subsets in SLE patients treated with or without BLM, with a focus on assessing MBC characteristics. Results: By employing HS flowcytometry, we established ...

Background The trend of, and the impact of major organ damage on the short- and longer-term survival of patients with systemic lupus erythematosus (SLE) globally over the past 60 years have not been ...

1 Department of Pediatric Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands 2 Department of Public Health, Erasmus University Medical Center ...

1 The Artic University of Norway, Department of Health Science, Tromsø, Norway 2 University Hospital of North Norway, Department of Rheumatology, Tromsø, Norway 3 UiT, The Artic University of Norway, ...

Objective Gout is characterised by severe interleukin (IL)-1-mediated joint inflammation induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine suppressing the ...

1 Wonkwang University Medical School, Internal Medicine, Iksan, Korea, Rep. of (South Korea) 2 Jeonbuk National University Medical School, Internal Medicine, Jeonju, Korea, Rep. of (South Korea) ...