The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

Getting hurt the Sunday before a Thursday night game gave San Francisco 49ers fans plenty of reason to be skeptical about ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

San Francisco 49ers rookie running back Isaac Guerendo sustained a foot injury and is questionable to return in Sunday's ...

The San Francisco 49ers may be down to their fourth-string RB after Isaac Guerendo suffered a foot injury against the Chicago ...

Isaac Guerendo's status for Thursday's game is "up in the air" after suffering a foot sprain in a win vs. the Bears.

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

According to ESPN's Adam Schefter, San Francisco 49ers rookie running back Isaac Guerendo is expected to suit up for Thursday ...

“49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being ...