Promethazine hydrochloride is a phenothiazine derivative that is structurally different from the antipsychotic phenothiazines. Promethazine is a histamine H 1-receptor antagonist with moderate ...

At intervals of five to nine days, healthy volunteers were given two 12.5-mg promethazine rectal suppositories, one 25-mg suppository, one 50-mg suppository, or 50 mg (10 mL) of promethazine oral ...

Pharmacokinetics of Promethazine Hydrochloride After Administration of Rectal ... Phenergan 12.5-mg rectal ... Phenergan 50-mg rectal suppository, Wyeth-Ayerst, lot 9940315. ...

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