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A nonsense mutation is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product. DNA is a chain of many smaller molecules called nucleotides. During protein ...
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder that almost exclusively affects women (1). After normal development, during the first 6 to 18 mo developmental stagnation and then ...
KIT-directed tyrosine kinase inhibitors (TKIs) are the key treatment for advanced GISTs, but TKI resistance because of secondary mutations often emerges. Novel approaches to overcome TKI resistance, ...
It was argued that the specification primarily described deletion mutations for one strain (S. Typhimurium) and failed to detail the implementation or expected results of insertion and substitution ...
"With the approval of Tagrisso, we have a new approach for managing unresectable Stage III non-small cell lung cancer with EGFR mutations," says Dr. Nathalie Daaboul, hemato-oncologist at the ...
dThe Center for Medicine in the Media, Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA eDepartment of Population Medicine, Harvard ...
Prevalence, Treatment Patterns, and Outcomes of Individuals with EGFR Positive Metastatic Non-Small Cell Lung Cancer in a Canadian Real-World Setting: A Comparison of Exon 19 Deletion, L858R, and Exon ...
On the other hand, only two studies have assessed genotypic and phenotypic resistance to furazolidone, hence the limited knowledge about mutations associated with resistance to this antibiotic.
School of Pharmaceutical Sciences, Tianjian Laboratory of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450001, P. R. China ...
aDepartment of Medicine, University of California San Diego, La Jolla, CA, USA bDepartment of Population Health and Disease Prevention, University of California Irvine, Irvine, CA, USA cHerbert ...
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