Objective Many societies recommend using estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) to determine metformin eligibility. We examined the potential impact of ...

(HealthDay News) — Use of estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) can expand metformin eligibility, according to a study published in the November issue of ...

(HealthDay News) — Use of estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) can expand metformin eligibility, according to a study published in the November issue of ...

05. No increases in risks for all-cause mortality, acidosis/serious infection, or cardiovascular disease were seen with metformin among patients with more severe renal impairment (eGFR ...

The researchers found an association between metformin use and acidosis only in patients with severely decreased kidney function, which is defined as an eGFR of less than 30 mL/min/1.73 m2.

Max saxagliptin 5mg/day and metformin ext-rel 2000mg/day. Renal impairment (eGFR 30–45mL/min/1.73m 2): not recommended; (eGFR <45mL/min/1.73m 2): max saxagliptin 2.5mg/day. Concomitant strong ...

Overall, Grams and her colleagues found an association between metformin use and acidosis only in patients with severely decreased kidney function, defined as an eGFR of less than 30 mL/min/1.73 m2.

Metformin was both safe and well tolerated in patients with autosomal dominant polycystic kidney disease (ADPKD), the phase II TAME PKD trial found. The parallel-group, randomized trial of 97 ...

Metformin is used in type 2 diabetes mellitus to decrease the amount of glucose produced by the liver and to increase the body’s response to insulin. In patients with renal failure (acute or chronic), ...