Researchers used base and prime editing to uncover new EGFR gene mutations that affect cancer progression and drug resistance ...

Researchers collected more than 5,000 samples from various dog breeds and wolves, using advanced RNA sequencing techniques to map gene expression and promoter structures. This extensive work ...

To determine the type and severity of a cancer, pathologists typically analyze thin slices of a tumor biopsy under a ...

To determine the type and severity of a cancer, pathologists typically analyze thin slices of a tumor biopsy under a microscope.

Nov. 8, 2024 — Scientists believe individuals of the most recently discovered 'hominin' group (the Denisovans) that interbred with modern day humans passed on some of their genes via multiple ...

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical ...

The map uncovers more about the mechanisms of drug resistance, highlights DNA changes that may be potential treatment biomarkers, and identifies promising combinations or second-line therapies.

Scientists have completed the first-ever genetic mapping of tumor cells from Taiwanese with breast cancer in a potential breakthrough for treatment and prevention of the disease. National Cancer ...

Here, Goode et al. build a T-cell eQTL map from primary sclerosing cholangitis and ulcerative colitis patients. Integrating eQTL and GWAS, they nominate effector genes at six genetic risk loci for ...

A variety of researchers are converging on the view that human evolution has been shaped by gene–culture interactions. Theoretical biologists use models to demonstrate that cultural processes ...

A large new analysis suggests that some people carry genetic variants that make them more likely to have female than male offspring. When you purchase through links on our site, we may earn an ...

titled “Base editing screens define the genetic landscape of cancer drug resistance mechanisms,” in which they concluded, “Our variant-to-function map has implications for patient ...