Turnovers defined the day for the 49ers, as they committed three in total, struggling to gain any momentum despite a touchdown from running back Isaac Guerendo. Meanwhile, Josh Allen and Amari ...

With Christian McCaffrey ruled out for the remainder of the game with a knee injury, the San Francisco 49ers run game went through Jordan Mason and rookie Isaac Guerendo on Sunday Night Football ...

With Christian McCaffrey unavailable because of leg injuries and Isaac Guerendo needing time to adjust to the pros, Mason broke out, having a few 100-yard games and being a decent rushing presence ...

Watch San Francisco 49ers tight end George Kittle's Week 14 highlights as he caught six passes for 151 yards against the Chicago Bears. Watch San Francisco 49ers quarterback Brock Purdy's best ...

Bucs rookie Bucky Irving (125th overall), 49ers rookie Isaac Guerendo (129th overall) and Jets rookie Braelon Allen (134th overall) all have had success this season. Yet, the Cowboys would do it all ...

Running back Isaac Guerendo is officially active for the the 49ers' pivotal "Thursday Night Football" game against the Los Angeles Rams despite dealing with a foot injury on a short week.

Isaac Guerendo injury update: 49ers RB goes to locker room in fourth quarter vs. Bears The 49ers backfield is further and further depleted. Running back Isaac Guerendo is the latest to suffer an ...

And the running game was good. Jordan Mason and Isaac Guerendo had emerged as an elite running-back tandem. Mason is one of the hardest runners in the NFL and Guerendo is one of the fastest.

The Binding of Isaac has received a new free DLC today, called Repentance+, that adds online multiplayer to the game. The new update allows up to four players to play together and run through the ...

Isaac Guerendo injury update: 49ers RB goes to locker room in fourth quarter vs. Bears The 49ers backfield is further and further depleted. Running back Isaac Guerendo is the latest to suffer an ...