The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

Christian McCaffrey and Jordan Mason both landed on IR after the 49ers lost to the Bills in Week 13. Isaac Guerendo will now ...

The injury to Jordan Mason is a tough blow for a 49ers team that was already preparing itself to miss more time without ...

Puskar) SANTA CLARA, Calif. (AP) — Ever since making the switch from high school receiver to running back in college, Isaac ...

49ers coach Chris Foerster believes Isaac Guerendo is ready for a bigger role in Week 14. When Christian McCaffrey landed on ...

Here's everything you need to know about the 49ers current RB depth chart following injuries to Christian McCaffrey and ...

The rookie running back showed off on an impressive drive that included a long catch and TD run against the Bears.

Isaac Guerendo is expected to step in as the San Francisco 49ers' starting running back after injuries to Christian McCaffrey and Jordan Mason. Guerendo, a versatile fourth-round rookie from ...

Early in the contest, starting running back Christian McCaffrey left the game ... They are as follows: Isaac Guerendo Patrick Taylor Jr. Guerendo, a fourth-round rookie out of Louisville, is ...

Isaac Guerendo didn’t start in college until his final game.. He starts at running back for the 49ers Sunday against Chicago.

The power structure is well represented on the All-Metro Conference team, led by honorary captains Jett Thomalla of Millard ...