Among them is gemcitabine, a pyrimidine antimetabolite. 13–17 Gemcitabine is well tolerated and can be safely used in patients with impaired renal function (GFR ≥ 30 mL/min). 18 Trial history and ...

A phase 2 trial in PAC demonstrated the safety and preliminary efficacy of TTFields therapy with gemcitabine with or without nab-paclitaxel. We report final data from PANOVA-3 (NCT03377491), the ...

In the 260-patient study, median event-free survival reached 16 months for patients assigned to PAXG, as compared with 10.2 months with the mFOLFIRINOX (5-fluorouracil, leucovorin, irinotecan ...

Doctors often use chemotherapy to treat pancreatic cancer that has spread. One of the drugs used is gemcitabine. Acelarin is a type of chemotherapy.It is a similar drug to gemcitabine, but scientists ...

See the UIL Texas high school baseball state championship schedule, pairings and game times. Check back for title game results at Dell Diamond in Round Rock.

500mg, 1g, 2g: pwd for inj after reconsti ... gemcitabine — 200mg, 1g, 2g: pwd for IV infusion after reconsti ...

Figure 1 Inhibition of AsPC-1 cell growth by OxA and/or gemcitabine.(A) Inhibition of AsPC-1 cell viability induced by 0.01 µM gemcitabine (gem), 0.1 µM OxA (OxA), or 0.01 µM gemcitabine plus 0.1 µM ...

Gemcitabine, a drug with established efficacy against a number of solid tumors, has therapeutic limitations due to its rapid metabolic inactivation. The aim of this study was the development of an ...

Nintedanib (BIBF1120) is a potent, oral, small-molecule tyrosine kinase inhibitor, also known as a triple angiokinase inhibitor, inhibiting three major signaling pathways involved in angiogenesis.

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...