Copyright 2024 The Associated Press. All Rights Reserved. San Francisco 49ers running back Christian McCaffrey (23) runs ...

It would appear Christian ... 49ers news, schedule, roster, stats, injury updates and more. McCaffrey suffered a knee injury early in the second quarter of the 49ers' "Sunday Night Football ...

San Francisco 49ers running back Christian McCaffrey's season might be over. The star running back will be placed on injured reserve after suffering a PCL injury in his left knee, 49ers coach Kyle ...

(AP Photo/Adrian Kraus) San Francisco 49ers running back Christian McCaffrey (23) runs against Buffalo Bills safety Taylor Rapp, bottom, during the first half of an NFL football game in Orchard ...

The 49ers thought the return of Christian ... on McCaffrey. He deserves credit for battling back from bilateral Achilles tendonitis and playing with no offseason. He clearly isn't in football ...

The San Francisco 49ers came into this game against the Bills decimated by injuries and Christian McCaffrey picked up one in the first half to further compound their problems. The running back ...

SANTA CLARA — There’s a running back renaissance taking place in the NFL and Christian McCaffrey ... me every day.” 49ers report card: ‘We’re finally playing team football’ The thought ...

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back did not return to Sunday’s snowy game in Buffalo after exiting with a ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

It would appear Christian ... back's season might be over. McCaffrey suffered a knee injury early in the second quarter of the 49ers' "Sunday Night Football" meeting with the Bills.