Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...

The 49ers injury woes continue at running back after Isaac Guerendo was carted off the field in the 1st quarter.

San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...

The last-place 49ers (6-11) lost seven of their final eight and did so with a generous defense that failed to produce a ...

Cardinals cornerback Max Melton exited Sunday's season finale against the 49ers with a wrist injury, and the club announced ...

The 49ers Faithful gladly bid adieu to 2024 and turn their attention to a new year featuring a new contract for Brock Purdy ...

Among those listed as “out” Friday by 49ers coach Kyle Shanahan were wide receiver Deebo Samuel (rib/wrist), cornerback ...

The San Francisco 49ers ended a disastrous 2024 NFL season on Sunday with plenty more things going horribly wrong against the Arizona Cardinals.

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...

The National Football League injury report, as provided by the league (OUT: Player will not play; DOUBTFUL: Player is ...