Clinical genetics involves the study ... pedigree analysis, disease locus mapping by linkage or homozygosity, karyotyping, genome sequencing and genotyping.

The function of CBFA1 during skeletal development was further elucidated by the generation of mutated mice in which the Cbfa1 gene locus was targeted. Loss of one Cbfa1 allele (+/-) leads to a ...

UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

In a nutshell All modern humans share DNA from two ancient populations that split 1.5 million years ago and reunited through ...

For decades, scientists were baffled by why thorny skates in the North Atlantic came in two distinct sizes. Despite extensive ...

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...