This dose-ranging study used the acute febrile sore throat model (oral temperature ≥38.0°C) to establish the lowest reliable antipyretic and analgesic dose of diclofenac potassium (6.25, 12.5 ...

Research Trusted Source suggests that taking diclofenac may increase the risk of heart problems. It may also impact gastrointestinal, kidney, and liver health.

Objectives To compare the efficacy and safety of topical non-steroidal anti-inflammatory drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA). Methods PubMed, Embase, ...

The Diclofenac Disaster. The principal culprit behind this ecological tragedy is the veterinary drug Diclofenac, commonly used in the 1990s to treat livestock. Though effective, Diclofenac residues in ...

Although diclofenac ranks among the most frequently detected pharmaceuticals in the urban water cycle, its environmental transformation reactions remain imperfectly understood. Biodegradation-induced ...

From 1975, with the introduction of the use of diclofenac for the treatment of inflammations, quantitative analytical procedures appeared in the literature for its determination in biological ...

We investigated the anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex (5.5 or 11 mg/kg) in male Wistar rats (180-300 g, N = 6) and compared it to free diclofenac ...

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