Finding help for quarterback Brock Purdy needs to be a priority for the San Francisco 49ers in the 2025 NFL draft. However, ...

The NFL Week 15 Thursday Night Football game between the Los Angeles Rams and San Francisco 49ers will be played at Levi's Stadium in Santa Clara, Calif. The Rams at 49ers game will be streamed on ...

Derrick Feldt, a 49ers fan who has beaten cancer twice, caught the attention of San Francisco star Christian McCaffrey before ...

Head coach Kyle Shanahan and defensive coordinator Nick Sorensen shared injury updates on RB Isaac Guerendo, DL Nick Bosa and more and discussed how the team is preparing for a short turnaround ahead ...

George Kittle is having one of the best seasons of his career. Deebo Samuel is not. On Tuesday in the 49ers locker room, ...

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

More and more you could make an argument the most dangerous job is that of running back for the San Francisco 49ers.

San Francisco 49ers running back Christian McCaffrey (23) runs against Buffalo Bills safety Taylor Rapp, bottom, during the first half of an NFL football game in Orchard Park, N.Y., Sunday ...

San Francisco 49ers head coach Kyle Shanahan reaffirmed his commitment to the organization after a 38-13 win over the Chicago Bears on Sunday. "I don't ...

No Christian McCaffrey has been no problem for the 49ers in the first quarter of Sunday's game against the Bears.

RB Christian McCaffrey looked to finally be taking off after his return from an Achilles injury but suffered a PCL injury ...

With Christian McCaffrey on the shelf, the 49ers will turn to RB Isaac Guerendo, and he will deliver in Week 14 against the Bears!