Furthermore, our mechanistic investigations have unveiled that DNAJ-PKAC localises to the centrosome, where it engages in a high-affinity interaction with PLK1. Our research advances the mechanistic ...

Centrosome amplification (CA) is highly prevalent in cancer. It is strongly associated with tumor progression and worse prognosis in a variety of different cancers. Preclinical studies have ...

Cancer cells often display centrosome amplification, requiring the kinesin KIFC1/HSET for centrosome clustering to prevent multipolar spindles and cell death. In parallel siRNA screens of ...

Optical amplification, which increases the average number of photons, is important in many quantum communication protocols. However, for amplification to be effective in the quantum regime ...

Corsi, of the University of Cambridge, found that “high toxicity tweets and those with right-leaning bias see heightened amplification” on X in a study examining posts about Covid-19 and ...

Prospective Study of Supplemental Screening With Contrast-Enhanced Mammography in Women With Elevated Risk of Breast Cancer: Results of the Prevalence Round In a tumor agnostic fashion, cfDNA for ...

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Centrosome amplification and aberrant expression of its associated proteins such as Polo-like kinases (PLKs), Aurora kinases (AURKs) and Cyclin-dependent kinases (CDKs) have been observed in various ...