For acute major bleeding within 18 hours after factor Xa inhibitor administration, a bolus and infusion of andexanet alfa (andexanet) reduces factor Xa activity, according to a study published online ...

A new study examines the effect of rapid infusion of 2meq/kg of sodium bicarbonate (NaHCO3) in an ovine model on gas exchange and coronary and cerebral perfusion in the immediate post-resuscitation ...

An individual patient-level meta-analysis shows that tenecteplase, a next-generation thrombolytic, is at least as effective ...

Currently in the HSCT setting, the recommended method of administration of i.v. tacrolimus is as a continuous 24 h infusion of 0.03–0.04 mg/kg per day, usually starting on day -2 of HSCT; with the aim ...

Doxapram (Dox) has been recently used in the treatment of apnea of the newborn. Currently Dox is given by continuous I.V. low dose infusion; this usually implies a slow onset of action. A bolus ...

At a recent meeting of the AAMI Healthcare Technology Safety Institute, researchers from the University of Toronto released a report that provides nine specific recommendations to reduce the risks ...

Chicago, IL - Canadian researchers compared the occurrence of uncommon adverse events in phase 2 versus phase 3 trials, using the example of intracranial hemorrhage rates in bolus thrombolysis trials.

Anthracycline-related cardiomyopathy in childhood cancer survivors and association with polymorphisms in the carbonyl reductase genes: A Children's Oncology Group study. Background: Continuous ...