With running backs Christian McCaffrey and Jordan Mason on IR, the 49ers turned to rookie RB Isaac Guerendo to start their ...

The 49ers are getting desperate at running back after three injuries. Here’s who is next up in Kyle Shanahan’s offense.

Now, it looks as though the 49ers may be down yet another running back, as Isaac Guerendo was forced out of Sunday’s game ...

Patric Taylor Jr. took over when Guerendo exited and punched in a late garbage-time touchdown. He finished with 25 yards on ...

Being prepared for what life throws at him is a specialty for 49ers running back Patrick Taylor Jr., whether it’s the ...

The 49ers might have to reach a little further down their depth chart to find another starting running back. Rookie running ...

Stafford is arguably the best quarterback in the NFL when he can operate from a clean pocket — he has thrown for 2,656 yards ...

The 49ers (5-7) will have a full-staff secondary today with the return of safety Talanoa Hufanga and starting cornerbacks ...

Patrick Taylor Jr. detailed the mentality the San Francisco 49ers had in their dominating win on Sunday over the Chicago ...

In the span of a week, the San Francisco 49ers are watching their running backs drop like flies. Superstar Christian ...

If the San Francisco 49ers want to defend their NFC West title, they must defeat the Los Angeles Rams in Week 15. However, the team enters Thursday Night Footba ...

San Francisco 49ers running back Isaac Guerendo has been diagnosed with a sprained foot, head coach Kyle Shanahan announced on Monday. The 24-year-old ...