The Arizona Cardinals' final game of the season is Sunday at State Farm Stadium against the San Francisco 49ers. The ...

Matt Maiocco hands out team grades from the San Francisco 49ers' 40-34 loss to the Detroit Lions on Monday at Levi's Stadium.

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The Arizona Cardinals face the San Francisco 49ers in their season finale and have made roster moves to prepare for the game ...

The 49ers (6-10) turned in a typical second-half letdown in all aspects of their 40-34 defeat to the Detroit Lions in ...

It looked in the middle of the season like the San Francisco 49ers and Arizona Cardinals may be playing for the NFC West ...

The San Francisco 49ers will start Joshua Dobbs at quarterback on Sunday when they travel to face the Arizona Cardinals on ...

The 49ers lost defensive tackle Javon Hargrave early with a torn triceps. Middle linebacker Fred Warner has played with an ...

The Arizona Cardinals did not have second-year receiver Michael Wilson. After suffering a hamstring injury Friday, making him questionable for the season finale against the San Francisco 49ers, he was ...

San Francisco quarterback Brock Purdy completed 65 percent of his 40 passes for 313 yards, two touchdowns, and an ...

The San Francisco 49ers entered their Week 18 finale on the road against the Arizona Cardinals with several starters ruled out. Quarterback Brock Purdy, receiver Deebo Samuel and cornerback Deommodore ...