By Simon Lewis and Matt Spetalnick WASHINGTON (Reuters) -When Marco Rubio arrives in Latin America this weekend on his first foreign trip as Donald Trump's secretary of state, he'll find a region reeling from the new administration's shock-and-awe approach to diplomacy.

Panama President José Raúl Mulino says there will be no negotiation with the United States over ownership of the Panama Canal.

Panamanian President Jose Raul Mulino ruled out discussing control of the Panama Canal with U.S. Secretary of State Marco Rubio when he visits the Central American country. "I cannot negotiate and much less open a process of negotiation on the Canal," Mulino said during his weekly press conference, saying the matter is "sealed."

Secretary of State Marco Rubio said on Thursday he had "zero doubt" that China has a contingency plan to shut down the Panama Canal in the event of a conflict with the U.S. and that Washington intends to address what it sees as a national security threat.

The new U.S. secretary of state will find a region reeling from the Trump administration's shock-and-awe approach to diplomacy.

Marco Rubio will head overseas late next week; he's also scheduled to visit Guatemala, El Salvador, Costa Rica and the Dominican Republic.

Secretary of State Marco Rubio says President Donald Trump's desire to acquire Greenland and retake control of the Panama Canal is driven by legitimate national security interests stemming from growing concerns about Chinese activity and influence in the Arctic and in Latin America.

Former U.S. senator from Florida Marco Rubio jumps into new role as secretary of state with flurry of phone calls, planned trip to Panama.

Amid Trump’s bid to acquire Greenland, Rep. Andy Ogles (R-TN) also stressed the need to properly compete with China and “send them back to their own hemisphere.” He added that Trump publicly expressing interest in Greenland is “broadcasting” that “America is great again.”

Secretary of State Marco Rubio asserts that President Trump’s interest in acquiring Greenland and reasserting control over the Panama Canal stems from legitimate national security threats posed by China’s growing influence in these strategic areas.

Panama President Jose Raul Mulino said Thursday there will be no negotiation with the United States over ownership of the Panama Canal, and he hopes US Secretary of State Marco Rubio's upcoming visit will allow them to focus on shared interests including migration and combating drug trafficking.