Drug treatment to reduce cholesterol to new target levels is now recommended in four moderate- to high-risk patient populations: patients who have already sustained a cardiovascular event, adult ...

This electronic resource aims to provide physicians with fast and easy access to practical guidelines linked to the best available research evidence. It covers a wide range of medical conditions and ...

Correspondence to Dr Feng Xie, Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada; fengxie{at}mcmaster.ca; Dr Pablo Alonso-Coello, Iberoamerican Cochran ...

The burden of death due to firearms is an ongoing public health problem in the USA. US men had a 21% life expectancy loss due to firearms compared with men from other countries.1 In 2016, 7.8% of the ...

Correspondence to Dr Amitava Banerjee, Institute of Health Informatics, University College London, London NW1 2DA, UK; ami.banerjee{at}ucl.ac.uk Contributors AB is the sole author. Funding This work ...

Quantifying the time-varying association between objectively measured physical activity and mortality in US older adults over a 12-year follow-up period: the NHANES 2003–2006 study ...

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Correspondence to Dr Juan Victor Ariel Franco, Research Department, Instituto Universitario del Hospital Italiano de Buenos Aires, 1199 Buenos Aires, Argentina; juanfranco{at}bmj.com ...

Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

Correspondence to Dr Elaine Lehane, Catherine McAuley School of Nursing and Midwifery, University College Cork, Cork T12 K8AF, Ireland; e.lehane{at}ucc.ie To highlight and advance clinical ...

Correspondence to: Dr An De Sutter, Department of Family Medicine and Primary Health Care, Ghent University, Ghent 9000, Belgium; an.desutter{at}UGent.be The authors searched CENTRAL, MEDLINE, EMBASE, ...

Correspondence to Sir Iain Chalmers, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK; ichalmers{at}jameslind.net We are surrounded by maelstroms of claims about the effects ...