Identifying novel molecular drivers of disease progression in heart failure (HF) is a high‐priority goal that may provide new therapeutic targets to improve patient outcomes. The authors investigated ...

Heart failure is a global public health issue that is associated with increasing morbidity and mortality. Previous studies have suggested that mitochondrial dysfunction plays critical roles in the ...

New Cornerstone Investigator Institute, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of ...

From the Departments of Emergency Medicine (I.S.), Medicine (G.N.), and Epidemiology and Community Medicine (G.W.), Clinical Epidemiology Program (V.D.M., L.N., J.B ...

An interesting target for cardiovascular drug development is Lp-PLA2, an enzyme that may act in the twilight zone between lipoprotein metabolism and inflammation. Lp-PLA2 is produced by macrophages ...

From the Departments of Internal Medicine III (A.A., C.H., C.U., A.O., A.M.Z., S.D.) and Neurology (S.L.), J.W. Goethe University, Frankfurt, Germany; Weizmann ...

Since 2016, hospitals have been able to document International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes for the National Institutes of Health Stroke Scale ...

From the Departments of Internal Medicine/Cardiology (H.S.H., Y.M., A.O., A.S., M.G.Y., K.C.H., G.W.D.), Institute of Molecular Pharmacology and Biophysics (I.B., A.S ...

Adding the difficulty of instructing ventilations over the telephone, Hallstrom et al 7 conducted a randomized study of emergency dispatch telephone instruction in BLS with or without mouth-to-mouth ...

Single-photon emission computed tomography (SPECT) using bone-avid tracers such as technetium-99m-labeled pyrophosphate (PYP), 99mTc-3,3-diphosphono-1,2-pyrophosphate (DPD), or 99mTc-hydroxymethylene ...

Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida School of Medicine, Tampa. For Sources of Funding and Disclosures, see page 1611.

Abstract: The identification of nitric oxide (•NO) as an endogenously produced free radical mediator of endothelial-dependent relaxation and host defense has fundamentally changed concepts of cell ...