ascopubs.org19d
Ibrutinib in Early-Stage Chronic Lymphocytic Leukemia: The Randomized, Placebo-Controlled, Double-Blind, Phase III CLL12 Trial
Erratum: ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma The German CLL Study Group conducted a ...
ascopubs.org11d
Pancreatic Adenocarcinoma: Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial
Zanubrutinib Versus Bendamustine and Rituximab in Patients With Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Median 5-Year Follow-Up of SEQUOIA The ESPAC4 trial showed that ...
ascopubs.org11d
Development and Validation of Dynamic 5-Year Breast Cancer Risk Model Using Repeated Mammograms
Current image-based long-term risk prediction models do not fully use previous screening mammogram images. Dynamic prediction models have not been investigated for use in routine care. We analyzed a ...
ascopubs.org11d
INDEPSO-ISPSM Consensus on Peritoneal Malignancies: Management of Colorectal Peritoneal Metastases
This manuscript reports the results of the Indian Network for Development of Peritoneal Surface Oncology and Indian Society of Peritoneal Surface Malignancies (INDEPSO-ISPSM) consensus that aimed to ...
ascopubs.org14d
Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database
Health-Related Quality of Life and Financial Burden in Ethiopian Patients With Chronic Myeloid Leukemia Receiving Tyrosine Kinase Inhibitors: A Cross-Sectional Study The marked underrepresentation of ...
ascopubs.org7d
Volumetric Breast Density Estimation From Three-Dimensional Reconstructed Digital Breast Tomosynthesis Images Using Deep Learning
We retrospectively analyzed 1,080 nonactionable three-dimensional (3D) reconstructed DBT screening examinations acquired between 2011 and 2016. Reference tissue segmentations were generated using ...
ascopubs.org12d
Short-Course Adjuvant Vaginal Cuff Brachytherapy in Early Endometrial Cancer Compared with Standard of Care (SAVE): A Randomized Clinical Trial
We conducted a prospective, randomized, multicenter trial examining short-course adjuvant VCB (11 Gy × two fractions at the surface) compared with standard regimens (7 Gy × three fractions at 0.5 cm ...
ascopubs.org14d
Application of Artificial Intelligence in Symptom Monitoring in Adult Cancer Survivorship: A Systematic Review
A total of 18,530 reports were identified, of which 41 met review criteria and were analyzed. Included studies were predominantly published between 2021 and 2023, originated in the United States (39.0 ...
ascopubs.org11d
Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations
Cancer-Control Outcomes of Patients With Metastatic Castration-Resistant Prostate Cancer With BRCA Gene or Tumor Suppressor Mutations Undergoing 177-Lutetium Prostate-Specific Membrane Antigen ...
ascopubs.org11d
Genomic Landscape of Malignant Phyllodes Tumors Identifies Subsets for Targeted Therapy
KRAS Variants Are Associated With Survival Outcomes and Genomic Alterations in Biliary Tract Cancers Malignant phyllodes tumors (MPTs) are rare fibroepithelial tumors of the breast with aggressive ...
ascopubs.org13d
Phase II Trial of the PARP Inhibitor, Niraparib, in BAP1 and Other DNA Damage Response Pathway-Deficient Neoplasms
Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations This was a phase II multicenter trial in which refractory solid ...
ascopubs.org13d
Actionability of Synthetic Data in a Heterogeneous and Rare Health Care Demographic: Adolescents and Young Adults With Cancer
Research on rare diseases and atypical health care demographics is often slowed by high interparticipant heterogeneity and overall scarcity of data. Synthetic data (SD) have been proposed as means for ...