PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...

Our brains contain billions of neurons and trillions of connections, and scientists are only beginning to understand the intricate process required to build this level of complexity. This includes ...

Phase II trial of the oral mTOR inhibitor everolimus (RAD001) for patients with relapsed or refractory lymphoma Mantle Cell Lymphoma (MCL) represents only 5–10% of all non-Hodgkins lymphomas, making ...

Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...

Researchers found that vitamin B3 (niacin) can suppress miR-93, a key driver of fatty liver disease. In mice, niacin restored ...

Dr. Yogesh Dwivedi authored a book chapter “microRNA Function and Dysregulation in Depression and Suicide” in Suicide Phenomenology and Neurobiology, Edited by: Keri Cannon and Thomas Hudzik.

In the October15th issue of G&D, Dr. Fen-Biao Gao and colleagues at UCSF report that microRNA-9a (mir-9a) regulates neural development in the fruit fly, Drosophila. Using loss-of-function analysis, Dr ...

Researchers identified microRNA-93 as a genetic driver of fatty liver disease and showed that vitamin B3 can effectively suppress it. This breakthrough suggests niacin could be repurposed as a ...

STOCKHOLM — The Nobel Prize in medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, a fundamental principle governing how gene activity is regulated.