The African trypanosome Trypanosoma brucei is a unicellular pathogen that causes lethal sleeping sickness in humans, which is a devastating and neglected tropical disease that is endemic to vast ...

Africa, Latin America, and certain regions of Asia face a heavy burden: diseases transmitted by insects, such as mosquitoes or tsetse flies. These often neglected diseases do not just devastate public ...

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...

This image shows a three-dimensional map of the basic structural unit in the parasite Trypanosoma brucei’s flagellum, with various mechanical and motor proteins labeled. Millions of people worldwide ...

Trypanosome parasites transmitted by tsetse flies cause devastating diseases in humans and livestock. Different subspecies infect different hosts: Trypanosoma brucei brucei infects cattle but is ...

A new study sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases in cattle and other animals establishes long-term infections in hosts.

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases ...

If left untreated, African Sleeping Sickness can causes meningoencephalitis, coma, and death. The disease is spread through tsetse flies that feed on infected hosts. In 2015, 84 percent of Trypanosoma ...