Jauan Jennings’ ejection and Isaac Guerendo’s cart-off knee injury added to the 49ers’ season-long macabre in Sunday’s 47-24 ...

The Detroit Lions capped the first unbeaten road schedule in team history on Monday night in San Francisco. The Lions ...

Ward announced his daughter’s death in an Instagram post on Oct. 29 and took time away from the team following the tragedy.

Charvarius Ward revealed how his "California trauma" could impact his free agency and whether he stays with the San Francisco 49ers.

The San Francisco 49ers offense racked up 436 total yards on Sunday against the Arizona Cardinals at State Farm Stadium ...

In the comment section of the post, Kittle posted a three-word message for Clark, saying, "Great days ahead!!" George Kittle ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted San Francisco 49ers 47-24.

San Francisco 49ers quarterback Brock Purdy has received an official diagnosis following injury on Monday Night Football.

The San Francisco 49ers appear to have dodged a bullet. In a season where not much has gone right for the defending NFC ...

Taylor signed a reserve/future contract with San Francisco on Monday. Taylor is very familiar with the 49ers after being selected by the organization in the fifth round of the 2017 NFL Draft.