This is the first comprehensive immunohistochemical analysis of the expression of several class I HDAC proteins (1, 2 and 3) in urothelial ... of patients with bladder cancer.

Combination therapy with enfortumab vedotin (Padcev) and pembrolizumab (Keytruda) was associated with durable responses and ...

Cancer of the urinary bladder is among the five most common malignancies worldwide. Urothelial cell carcinomas ... we describe the analysis of IL-8, MMP-9 and Syndecan in a validation phase ...

Oct. 9, 2024 — How bladder cancer originates and progresses has been illuminated as never before. Researchers found that antiviral enzymes that mutate the DNA of normal and cancer cells are key ...

You get bladder cancer when bladder cells become abnormal and grow out of control. Over time, a tumor forms. To find out whether you have bladder cancer, the first thing your doctor probably will ...

Metastatic urothelial cancer exhibits substantial molecular heterogeneity compared with the primary tumour, complicating the development of accurate biomarkers. Pre-treatment metastatic biopsies ...

Findings from the international FORT-2 clinical trial showed that a ... and are associated with improved survival. In ...

Johnson & Johnson has announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorization for BALVERSA®▼ (erdafitinib) as a monotherapy for the treatment ...

The move affects the accelerated approval for Trodelvy in advanced urothelial cancer ... Trodelvy earned its bladder cancer nod in 2021 based on single-arm, phase 2 data showing the drug triggered ...

Much of the information on our bladder cancer webpages applies to these cancers, too. Our patients with bladder or other urothelial cancer often join clinical trials — led by world-renowned doctors ...

Bladder cancer affects over 52,000 men and women in the United States on an annual basis, and more than 12,000 people die each year from this disease. It is the fourth most common cancer in men in ...