Pyruvate dehydrogenase complex (PDC) deficiency is a mitochondrial disorder arising from loss-of-function alterations in the multienzyme assembly that converts glycolytic pyruvate into acetyl-CoA, the ...
Pyruvate kinase deficiency is a rare, hereditary, chronic condition that is associated with hemolytic anemia. In a phase 2 study, mitapivat, an oral, first-in-class activator of erythrocyte pyruvate ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
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