Homologous recombination (HR) is central to the template-based repair of DNA double-strand breaks, maintaining genome integrity 1,2,3,4. A central reaction in HR is the strand exchange, in which the ...
Fast, accurate antibody structure prediction from deep learning on massive set of natural antibodies
Antibodies have the capacity to bind a diverse set of antigens, and they have become critical therapeutics and diagnostic molecules. The binding of antibodies is facilitated by a set of six ...
Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...
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