Agomelatine (Valdoxan), an oral antidepressant, has been available in some other countries since 2009, though you can’t get this medication in the United States. You take agomelatine as a 25-mg ...

Following comprehensive pharmacological evaluation and extensive clinical trials, agomelatine (Valdoxan/Thymanax ... Like all other drugs, agomelatine remains a work in progress.

Overall, 71.75% of patients achieved a response to Valdoxan, versus 64.52% on SSRIs/SNRI, “a statistically significant difference”, and the Servier drug also performed significantly better in patients ...

Back in April the companies followed it up with head-to-head data comparing Brintellix with agomelatine, which Servier sells in Europe as Valdoxan. The drug never made it onto the U.S. market.

According to Lundbeck, this trial demonstrated that Brintellix was significantly superior to Valdoxan based on certain depression symptom scales. The drug works by its ability to inhibit the serotonin ...