A new form of the disease in mice that does not cause the sponge-like brain deterioration typically seen in prion diseases has been observed by NIH scientists. A new form of the disease in mice ...

“I love the brain,” she enthused ... where she was introduced to the fascinating field of prions. Prion diseases are characterized by abnormal folding of the host’s naturally-occurring prion protein, ...

Newly emergent prion diseases such as bovine spongiform encephalopathy, variant Creutzfeldt–Jakob disease (CJD), and chronic wasting disease are a source of critical concern to physicians ...

Prions, which are a special class of proteins, are best known as causative factors for mad cow and other neurodegenerative diseases ... and very positive roles in brain function.

Those proteins then clump up in the brain and cause brain damage. Prion diseases, which include mad cow disease, are always fatal. In deer, the illness can exist for up to two years before ...

The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60%. There is currently no cure for ...

After eliminating some potential causes, he began to suspect that a new bovine disease was emerging. Clumps of killer rogue prion proteins form in the brain, and make holes, causing it to look ...

Some rare forms of dementia, including Creutzfeldt-Jakob disease (CJD) are caused by a type of protein called a prion. In these conditions, the prions misfold into a toxic form and then spread ...

The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60 percent. There is currently no cure ...