A team of scientists and physicians at Mass General Brigham has developed a single-dose oral cholera vaccine and tested it in a phase 1 clinical trial, with results published in The Lancet Infectious ...

Vibrio cholerae presents a unique model of bacterial genome organisation through its bipartite genome, comprising two distinct chromosomes that replicate in a carefully orchestrated manner. The ...

Unique immune component has kept one strain of cholera on top for more than 60 years. A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, ...

Experts have used a cutting-edge computational approach to discover the genetic factors that make the bacteria behind cholera so dangerous -- which could be key to preventing this deadly disease. The ...

Karl Klose, director of The South Texas Center for Emerging Infectious Diseases (STCEID) and the Robert J. Kleberg, Jr. and Helen C. Kleberg College of Sciences Endowed Professor, coauthored a ...

The evolutionary history of the pandemic Vibrio cholerae lineage shows that its emergence has not been linear, but shaped by several key genetic bottlenecks that explain its rarity. From a group of ...

The world is still in its seventh cholera pandemic, which has been surging since 2021, and case rates in various countries continue to be high. The disease is usually caused when water or food ...

Natural antimicrobials called microcins are produced by bacteria in the gut and show promise in fighting infection. On the left, a Vibrio cholerae strain that produces the antimicrobial MvcC (center) ...

A new study uncovers how the interplay between Sargassum spp., plastic marine debris and Vibrio bacteria creates the perfect “pathogen” storm that has implications for both marine life and public ...

The African CDC has recently warned of a surge in cholera cases across the continent. Cholera, caused by certain strains of V. cholerae, is a waterborne infection that spreads rapidly, particularly in ...