Novel generative AI model enables atomic-scale prediction of protein-protein interactions

Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building ...
Hackaday

ForceGen: Using A Diffusion Model To Help Design Novel Proteins

Although proteins are composed out of only a small number of distinct amino acids, this deceptive simplicity quickly vanishes when considering the many possible sequences across a protein, not to ...
Phys.org

AI diffusion models tailor drug molecules to custom-fit protein targets, speeding drug development and evaluation

University of Virginia School of Medicine scientists have developed a bold new approach to drug development and discovery that could dramatically accelerate the creation of new medicines. UVA's ...
GEN

BindCraft AI Model Achieves One-Shot Functional Protein Design

For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on ...
pharmaphorum

Zuckerberg, Chan's Biohub launches protein 'world model'

Non-profit research organisation Biohub has released what it claims is an AI-powered "world model" of protein biology that can drive the prediction, design, and discovery of new therapies. The ...
Phys.org

AI model enables reliable and accurate protein-ligand complex prediction

Understanding protein–ligand interactions is fundamental to molecular biology and biochemistry. These interactions are at the heart of many cellular processes, from enzyme catalysis to signal ...
GEN

Gero’s Structure-Free AI Model Generates Small Molecules from Protein Sequences

Gero, a biotechnology company developing novel therapeutics for aging and chronic diseases, has released ProtoBind-Diff, a novel masked diffusion language model that generates drug-like molecules for ...
National Academies of Sciences%2c Engineering%2c and Medicine

The Age of AI in the Life Sciences: Benefits and Biosecurity Considerations

This review provides an overview of artificial intelligence–enabled biological models, focusing on their applications in designing biological molecules and systems. We review foundation models that ...
Healio

Protein-based model improves lung cancer prediction in those with smoking history

A model based on proteins vs. a questionnaire had higher discrimination in predicting lung cancer risk in individuals with a smoking history, according to data presented at the American Thoracic ...