Pattern recognition receptors (PRRs) are expressed by cells in the body in order to sense molecules that are associated with infection or tissue damage. They are important for activating the ...

Cite this: Receptor for Advanced Glycation End ... seen as damaging proinflammatory pathways. Complex patterns of alternative RAGE transcription have been identified with the potential to generate ...

HMGB1's interactions with its primary receptors, RAGE and TLR4, are essential to its role in liver disease. Upon binding, these receptors initiate pro-inflammatory signaling pathways such as the ...