Cathepsin K readily degrades type I collagen, the major component of the organic bone matrix. With such a major role in the initial process of bone resorption, cathepsin K has become a therapeutic ...

The researchers were able to create such systems by combining organic and inorganic matrix components, including collagen and the bone mineral hydroxyapatite, in a manner that mimicked ...

The global demineralized bone matrix (DBM) market is experiencing sustained expansion as it solidifies its role as a vital component in orthopedic and regenerative medicine. Valued at USD 1.83 billion ...

The organic matrix is mainly comprised of collagen type 1 amongst other proteins. Bones contain marrow and maintain a calcium reservoir. Common bone diseases associated with aging are osteoporosis ...

The removal process left behind stretchy bone matrix material that, when examined microscopically, seemed to show blood vessels, osteocytes, or bone building cells, and other recognizable organic ...

Now, an interdisciplinary Cornell team has identified a new mechanism regulating tumor growth in the skeleton, the primary site of breast cancer metastasis: mineralization of the bone matrix, a ...